Advance on drug metabolism analysis method.

Mucoadhesive Vaginal Drug Delivery System: a Review on Advance Status

Mucoadhesive delivery systems offer several advantages over other oral controlled release systems by virtue of prolongation of residence time of drug, its targeting, and localization of the dosage form at a specific site. These advantages include bypass of first pass metabolism of the drug and hence more concentration of the drug is available for absorption. Mucoadhesion occurs between two surf...

The spurious advance of antipsychotic drug therapy.

Laming. The Victoria Climbie inquiry: report of an inquiry by Lord Laming. January, 2003. http://www.victoria-c1imbie-inquiry.org.uk/nnreport/ nnreport.htm (accessed Nov 13, 2008). BBC News Channel. Men found guilty of baby's death. Nov 11, 2008. http:// news.bbc.co.uk/1/hi/england/london/7706598.stm (accessed Nov 17, 2008). Gilbert R, Spatz Widom C. Browne K, Fergusson D, Webb E, Janson S. Bur...

Immune Monitoring Insights to Advance Drug Development

While the immune system protects organisms from infections, it can also react adversely to certain therapeutic interventions such as biologics that target various components of the immune system. Monitoring the responsiveness of the immune system to therapeutic interventions is crucial. This process, called immune monitoring, helps determine the safety and efficacy of therapeutic agents like va...

Principles of Drug Metabolism

Xenobiotic metabolism, which includes drug metabolism, has become a major pharmacological science with particular relevance to biology, therapeutics and toxicology. Drug metabolism is also of great importance inmedicinal chemistry because it influences in qualitative, quantitative, and kinetic terms the deactivation, activation, detoxification, and toxification of the vast majority of drugs. As...

Phase II Drug Metabolism